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CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice
Targeting solid tumors must overcome several major obstacles, in particular, the identification of elusive tumor-specific antigens. Here, we devise a strategy to help identify tumor-specific epitopes. Glypican 2 (GPC2) is overexpressed in neuroblastoma. Using RNA sequencing (RNA-seq) analysis, we sh...
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| Publicado no: | Cell Rep Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8233664/ https://ncbi.nlm.nih.gov/pubmed/34195677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100297 |
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