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Astrocytic apoE4 and tau: Deadly combination for neurons
New data from Wang and colleagues(1) suggest that astrocyte-derived apoE4 drives tau-mediated neurodegeneration. This research highlights how a genetic risk factor for Alzheimer’s disease is a major determinant of neurodegeneration in tau-expressing neurons by regulating non-cell-autonomous pathways...
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| Udgivet i: | Cell Rep Med |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8233647/ https://ncbi.nlm.nih.gov/pubmed/34195681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100316 |
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