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ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism
Alzheimer’s disease (AD) risk gene ApoE4 perturbs brain lipid homeostasis and energy transduction. However, the cell-type-specific mechanism of ApoE4 in modulating brain lipid metabolism is unclear. Here, we describe a detrimental role of ApoE4 in regulating fatty acid (FA) metabolism across neuron...
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| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7837265/ https://ncbi.nlm.nih.gov/pubmed/33406436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108572 |
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