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Structure and transport mechanism of P5B-ATPases

In human cells, P5B-ATPases execute the active export of physiologically important polyamines such as spermine from lysosomes to the cytosol, a function linked to a palette of disorders. Yet, the overall shape of P5B-ATPases and the mechanisms of polyamine recognition, uptake and transport remain el...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Li, Ping, Wang, Kaituo, Salustros, Nina, Grønberg, Christina, Gourdon, Pontus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233418/
https://ncbi.nlm.nih.gov/pubmed/34172751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24148-y
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