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Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport

Cu(+)-specific P-type ATPase membrane protein transporters regulate cellular copper levels. The lack of crystal structures in Cu(+)-binding states has limited our understanding of how ion entry and binding are achieved. Here, we characterize the molecular basis of Cu(+) entry using molecular-dynamic...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Grønberg, Christina, Sitsel, Oleg, Lindahl, Erik, Gourdon, Pontus, Andersson, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153542/
https://ncbi.nlm.nih.gov/pubmed/27926843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.020
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