Activity of trastuzumab emtansine (T-DM1) in 3D cell culture

BACKGROUND: Cell spheroids and aggregates generated from three-dimensional (3D) cell culture methods are similar to in vivo tumors in terms of tissue morphology, biology, and gene expression, unlike cells grown in 2D cell cultures. Breast cancer heterogeneity is one of the main drug resistant mechan...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res Treat
Prif Awduron: Boyer, Jean Zheng, Phillips, Gail D. Lewis, Nitta, Hiro, Garsha, Karl, Admire, Brittany, Kraft, Robert, Dennis, Eslie, Vela, Elizabeth, Towne, Penny
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2021
Pynciau:
Preclinical Study
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233276/
https://ncbi.nlm.nih.gov/pubmed/34091830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-021-06272-x
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