Activity of trastuzumab emtansine (T-DM1) in 3D cell culture

BACKGROUND: Cell spheroids and aggregates generated from three-dimensional (3D) cell culture methods are similar to in vivo tumors in terms of tissue morphology, biology, and gene expression, unlike cells grown in 2D cell cultures. Breast cancer heterogeneity is one of the main drug resistant mechan...

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Bibliografische gegevens
Gepubliceerd in:Breast Cancer Res Treat
Hoofdauteurs: Boyer, Jean Zheng, Phillips, Gail D. Lewis, Nitta, Hiro, Garsha, Karl, Admire, Brittany, Kraft, Robert, Dennis, Eslie, Vela, Elizabeth, Towne, Penny
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2021
Onderwerpen:
Preclinical Study
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233276/
https://ncbi.nlm.nih.gov/pubmed/34091830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-021-06272-x
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