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Activity of trastuzumab emtansine (T-DM1) in 3D cell culture
BACKGROUND: Cell spheroids and aggregates generated from three-dimensional (3D) cell culture methods are similar to in vivo tumors in terms of tissue morphology, biology, and gene expression, unlike cells grown in 2D cell cultures. Breast cancer heterogeneity is one of the main drug resistant mechan...
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| Publicado no: | Breast Cancer Res Treat |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8233276/ https://ncbi.nlm.nih.gov/pubmed/34091830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-021-06272-x |
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