NFAT signaling in human mesenchymal stromal cells affects extracellular matrix remodeling and antifungal immune responses

Mesenchymal stromal cells (MSCs) combined with calcineurin-nuclear factor of activated T cell (CN-NFAT) inhibitors are being tested as a treatment for graft-versus-host disease (GvHD). The immunosuppressive properties of MSCs seem beneficial; however, their response during fungal infection, which is...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Tidu, Federico, De Zuani, Marco, Jose, Shyam Sushama, Bendíčková, Kamila, Kubala, Lukáš, Caruso, Frank, Cavalieri, Francesca, Forte, Giancarlo, Frič, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233198/
https://ncbi.nlm.nih.gov/pubmed/34195564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102683
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