Calcineurin inhibitors reduce NFAT‐dependent expression of antifungal pentraxin‐3 by human monocytes

Calcineurin (CN) inhibitors are effective clinical immunosuppressants but leave patients vulnerable to potentially fatal fungal infections. This study tested the hypothesis that CN inhibition interferes with antifungal immune defenses mediated by monocytes. We showed that NFAT is expressed by human...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Bendíčková, Kamila, Tidu, Federico, De Zuani, Marco, Kohoutková, Marcela Hortová, Andrejčinová, Ivana, Pompeiano, Antonio, Bělášková, Silvie, Forte, Giancarlo, Zelante, Teresa, Frič, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7064969/
https://ncbi.nlm.nih.gov/pubmed/30934147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.4VMA0318-138R
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados