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Monomeric bile acids modulate the ATPase activity of detergent-solubilized ABCB4/MDR3

ABCB4, also called multidrug-resistant protein 3 (MDR3), is an ATP binding cassette transporter located in the canalicular membrane of hepatocytes that specifically translocates phosphatidylcholine (PC) lipids from the cytoplasmic to the extracellular leaflet. Due to the harsh detergent effect of bi...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Kroll, Tim, Smits, Sander H.J., Schmitt, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233136/
https://ncbi.nlm.nih.gov/pubmed/34022183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100087
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