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Detergent Screening and Purification of the Human Liver ABC Transporters BSEP (ABCB11) and MDR3 (ABCB4) Expressed in the Yeast Pichia pastoris

The human liver ATP-binding cassette (ABC) transporters bile salt export pump (BSEP/ABCB11) and the multidrug resistance protein 3 (MDR3/ABCB4) fulfill the translocation of bile salts and phosphatidylcholine across the apical membrane of hepatocytes. In concert with ABCG5/G8, these two transporters...

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Detalhes bibliográficos
Main Authors: Ellinger, Philipp, Kluth, Marianne, Stindt, Jan, Smits, Sander H. J., Schmitt, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617136/
https://ncbi.nlm.nih.gov/pubmed/23593265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060620
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