Wordt geladen...
Erlotinib and Trametinib in Patients With EGFR-Mutant Lung Adenocarcinoma and Acquired Resistance to a Prior Tyrosine Kinase Inhibitor
Inhibition of the MEK/ERK pathway is critical for Bcl-2-like protein 11 (BIM)-mediated epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)-induced apoptosis, and dysregulation of this pathway may be a mechanism of acquired resistance. Therefore, MEK inhibition with trametinib and...
Bewaard in:
| Gepubliceerd in: | JCO Precis Oncol |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society of Clinical Oncology
2021
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8232136/ https://ncbi.nlm.nih.gov/pubmed/34250388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.20.00315 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|