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Revealing the Structural Plasticity of SARS-CoV-2 nsp7 and nsp8 Using Structural Proteomics

Coronavirus (CoV) non-structural proteins (nsps) assemble to form the replication-transcription complex (RTC) responsible for viral RNA synthesis. nsp7 and nsp8 are important cofactors of the RTC, as they interact and regulate the activity of RNA-dependent RNA polymerase and other nsps. To date, no...

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Podrobná bibliografie
Vydáno v:J Am Soc Mass Spectrom
Hlavní autoři: Courouble, Valentine V., Dey, Sanjay Kumar, Yadav, Ruchi, Timm, Jennifer, Harrison, Jerry Joe E. K., Ruiz, Francesc X., Arnold, Eddy, Griffin, Patrick R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231661/
https://ncbi.nlm.nih.gov/pubmed/34121407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jasms.1c00086
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