Anti-Tumoral Effects of a (1H-Pyrrol-1-yl)Methyl-1H-Benzoimidazole Carbamate Ester Derivative on Head and Neck Squamous Carcinoma Cell Lines

Nocodazole is an antineoplastic agent that exerts its effects by depolymerizing microtubules. Herein we report a structural analog of nocodazole, a (1H-pyrrol-1-yl)methyl-1H-benzoimidazole carbamate ester derivative, named RDS 60. We evaluated the antineoplastic properties of RDS 60 in two human hea...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Principais autores: Nicolai, Alice, Madia, Valentina Noemi, Messore, Antonella, De Vita, Daniela, De Leo, Alessandro, Ialongo, Davide, Tudino, Valeria, Tortorella, Elisabetta, Scipione, Luigi, Taurone, Samanta, Pergolizzi, Tiziano, Artico, Marco, Di Santo, Roberto, Costi, Roberta, Scarpa, Susanna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231569/
https://ncbi.nlm.nih.gov/pubmed/34204738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph14060564
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