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Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors

SIMPLE SUMMARY: Anti-angiogenesis agents have shown anti-cancer activity by preventing blood vessel ingrowth, thereby limiting tumour growth and metastasis. Although these molecules lead to prolonged overall survival of cancer patients, therapy resistance is easily acquired. Therefore, novel inhibit...

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Publicat a:Cancers (Basel)
Autors principals: Ma, Jin, Ren, Jiang, Thorikay, Midory, van Dinther, Maarten, Sanchez-Duffhues, Gonzalo, Caradec, Josselin, Benderitter, Pascal, Hoflack, Jan, ten Dijke, Peter
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231556/
https://ncbi.nlm.nih.gov/pubmed/34204675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13122951
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