A 2-Dose AERAS-402 Regimen Boosts CD8(+) Polyfunctionality in HIV-Negative, BCG-Vaccinated Recipients

Despite the widespread use of BCG, tuberculosis (TB) remains a global threat. Existing vaccine candidates in clinical trials are designed to replace or boost BCG which does not provide satisfying long-term protection. AERAS-402 is a replication-deficient Ad35 vaccine encoding a fusion protein of the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sivakumaran, Dhanasekaran, Blatner, Gretta, Bakken, Rasmus, Hokey, David, Ritz, Christian, Jenum, Synne, Grewal, Harleen M. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231292/
https://ncbi.nlm.nih.gov/pubmed/34177914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.673532
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