Metformin Targets Foxo1 to Control Glucose Homeostasis

Metformin is the first-line pharmacotherapy for type 2 diabetes mellitus (T2D). Metformin exerts its glucose-lowering effect primarily through decreasing hepatic glucose production (HGP). However, the precise molecular mechanisms of metformin remain unclear due to supra-pharmacological concentration...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Guo, Xiaoqin, Li, Xiaopeng, Yang, Wanbao, Liao, Wang, Shen, James Zheng, Ai, Weiqi, Pan, Quan, Sun, Yuxiang, Zhang, Kebin, Zhang, Rui, Qiu, Yuyang, Dai, Qian, Zheng, Hongting, Guo, Shaodong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231152/
https://ncbi.nlm.nih.gov/pubmed/34208360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060873
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