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Metformin Targets Foxo1 to Control Glucose Homeostasis

Metformin is the first-line pharmacotherapy for type 2 diabetes mellitus (T2D). Metformin exerts its glucose-lowering effect primarily through decreasing hepatic glucose production (HGP). However, the precise molecular mechanisms of metformin remain unclear due to supra-pharmacological concentration...

詳細記述

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書誌詳細
出版年:Biomolecules
主要な著者: Guo, Xiaoqin, Li, Xiaopeng, Yang, Wanbao, Liao, Wang, Shen, James Zheng, Ai, Weiqi, Pan, Quan, Sun, Yuxiang, Zhang, Kebin, Zhang, Rui, Qiu, Yuyang, Dai, Qian, Zheng, Hongting, Guo, Shaodong
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8231152/
https://ncbi.nlm.nih.gov/pubmed/34208360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060873
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