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Metformin Targets Foxo1 to Control Glucose Homeostasis
Metformin is the first-line pharmacotherapy for type 2 diabetes mellitus (T2D). Metformin exerts its glucose-lowering effect primarily through decreasing hepatic glucose production (HGP). However, the precise molecular mechanisms of metformin remain unclear due to supra-pharmacological concentration...
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| 出版年: | Biomolecules |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8231152/ https://ncbi.nlm.nih.gov/pubmed/34208360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060873 |
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