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Hepatic Suppression of Foxo1 and Foxo3 Causes Hypoglycemia and Hyperlipidemia in Mice

Dysregulation of blood glucose and triglycerides are the major characteristics of type 2 diabetes mellitus. We sought to identify the mechanisms regulating blood glucose and lipid homeostasis. Cell-based studies established that the Foxo forkhead transcription factors Forkhead box O (Foxo)-1, Foxo3,...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Zhang, Kebin, Li, Ling, Qi, Yajuan, Zhu, Xiaoping, Gan, Boyi, DePinho, Ronald A., Averitt, Travis, Guo, Shaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393302/
https://ncbi.nlm.nih.gov/pubmed/22147007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1527
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