Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice

The transcription factor forkhead box O1 (FoxO1) is a key mediator in the insulin signaling pathway and controls multiple physiological functions, including hepatic glucose production (HGP) and pancreatic β-cell function. We previously demonstrated that S256 in human FOXO1 (FOXO1-S256), equivalent t...

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Pubblicato in:Endocrinology
Autori principali: Zhang, Kebin, Guo, Xiaoqin, Yan, Hui, Wu, Yuxin, Pan, Quan, Shen, James Zheng, Li, Xiaopeng, Chen, Yunmei, Li, Ling, Qi, Yajuan, Xu, Zihui, Xie, Wei, Zhang, Weiping, Threadgill, David, He, Ling, Villarreal, Daniel, Sun, Yuxiang, White, Morris F, Zheng, Hongting, Guo, Shaodong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482038/
https://ncbi.nlm.nih.gov/pubmed/30951171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00853
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