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A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes
Protein arginine methyltransferases (PRMTs) play important roles in transcription, splicing, DNA damage repair, RNA biology, and cellular metabolism. Thus, PRMTs have been attractive targets for various diseases. In this study, we reported the design and synthesis of a potent pan-inhibitor for PRMTs...
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| Опубликовано в: : | Biomolecules |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8230315/ https://ncbi.nlm.nih.gov/pubmed/34201091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060854 |
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