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Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization

NK cells are the first line of defense against viruses and malignant cells, and their natural functionality makes these cells a promising candidate for cancer cell therapy. The genetic modifications of NK cells, allowing them to overcome some of their inherent limitations, such as low proliferative...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomedicines
Hauptverfasser: Streltsova, Maria A., Ustiuzhanina, Maria O., Barsov, Eugene V., Kust, Sofya A., Velichinskii, Rodion A., Kovalenko, Elena I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229856/
https://ncbi.nlm.nih.gov/pubmed/34207853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060662
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