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Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy

Telomeres are specialized repeats, present at the end of chromosomes, whose loss during cell division is followed by growth arrest, a central mechanism of replicative senescence in human cells. Telomere length in stem cells is maintained by telomerase, a specialized reverse transcriptase, whose func...

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Bibliografiske detaljer
Hovedforfatter: Barsov, Eugene V
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120014/
https://ncbi.nlm.nih.gov/pubmed/21395382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.10.107
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