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Telomerase and primary T cells: biology and immortalization for adoptive immunotherapy
Telomeres are specialized repeats, present at the end of chromosomes, whose loss during cell division is followed by growth arrest, a central mechanism of replicative senescence in human cells. Telomere length in stem cells is maintained by telomerase, a specialized reverse transcriptase, whose func...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120014/ https://ncbi.nlm.nih.gov/pubmed/21395382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.10.107 |
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