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Differentiation of immortal cells inhibits telomerase activity.

Telomerase, a ribonucleic acid-protein complex, adds hexameric repeats of 5'-TTAGGG-3' to the ends of mammalian chromosomal DNA (telomeres) to compensate for the progressive loss that occurs with successive rounds of DNA replication. Although somatic cells do not express telomerase, germ c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sharma, H W, Sokoloski, J A, Perez, J R, Maltese, J Y, Sartorelli, A C, Stein, C A, Nichols, G, Khaled, Z, Telang, N T, Narayanan, R
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC40353/
https://ncbi.nlm.nih.gov/pubmed/8618897
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