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Selection of Human Cytomegalovirus Mutants with Resistance against PDGFRα-Derived Entry Inhibitors

The human cytomegalovirus (HCMV) infects fibroblasts via an interaction of its envelope glycoprotein gO with the cellular platelet-derived growth factor receptor alpha (PDGFRα), and soluble derivatives of this receptor can inhibit viral entry. We aimed to select mutants with resistance against PDGFR...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Laib Sampaio, Kerstin, Lutz, Carolin, Engels, Rebecca, Stöhr, Dagmar, Sinzger, Christian
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8229732/
https://ncbi.nlm.nih.gov/pubmed/34201364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v13061094
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