A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells

Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral strategies may include inhibition of entry. We show that solubl...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Stegmann, Cora, Hochdorfer, Daniel, Lieber, Diana, Subramanian, Narmadha, Stöhr, Dagmar, Laib Sampaio, Kerstin, Sinzger, Christian
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389858/
https://ncbi.nlm.nih.gov/pubmed/28403220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006273
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires