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A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells

Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral strategies may include inhibition of entry. We show that solubl...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Stegmann, Cora, Hochdorfer, Daniel, Lieber, Diana, Subramanian, Narmadha, Stöhr, Dagmar, Laib Sampaio, Kerstin, Sinzger, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389858/
https://ncbi.nlm.nih.gov/pubmed/28403220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006273
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