Emergence of Mechano-Sensitive Contraction Autoregulation in Cardiomyocytes

The heart has two intrinsic mechanisms to enhance contractile strength that compensate for increased mechanical load to help maintain cardiac output. When vascular resistance increases the ventricular chamber initially expands causing an immediate length-dependent increase of contraction force via t...

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Bibliographic Details
Published in:Life (Basel)
Main Authors: Izu, Leighton, Shimkunas, Rafael, Jian, Zhong, Hegyi, Bence, Kazemi-Lari, Mohammad, Baker, Anthony, Shaw, John, Banyasz, Tamas, Chen-Izu, Ye
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227646/
https://ncbi.nlm.nih.gov/pubmed/34072584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life11060503
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