KN-93 inhibits I(Kr) in mammalian cardiomyocytes

Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibitor KN-93 is widely used in multiple fields of cardiac research especially for studying the mechanisms of cardiomyopathy and cardiac arrhythmias. Whereas KN-93 is a potent inhibitor of CaMKII, several off-target effects have also been fou...

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Vydáno v:J Mol Cell Cardiol
Hlavní autoři: Hegyi, Bence, Chen-Izu, Ye, Jian, Zhong, Shimkunas, Rafael, Izu, Leighton T., Banyasz, Tamas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689637/
https://ncbi.nlm.nih.gov/pubmed/26463508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2015.10.012
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