Bioreactor Suspension Culture: Differentiation and Production of Cardiomyocyte Spheroids From Human Induced Pluripotent Stem Cells

Human induced-pluripotent stem cells (hiPSCs) can be efficiently differentiated into cardiomyocytes (hiPSC-CMs) via the GiWi method, which uses small-molecule inhibitors of glycogen synthase kinase (GSK) and tankyrase to first activate and then suppress Wnt signaling. However, this method is typical...

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Detalhes bibliográficos
Publicado no:Front Bioeng Biotechnol
Main Authors: Kahn-Krell, Asher, Pretorius, Danielle, Ou, Jianfa, Fast, Vladimir G., Litovsky, Silvio, Berry, Joel, Liu, Xiaoguang (Margaret), Zhang, Jianyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Bioengineering and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226172/
https://ncbi.nlm.nih.gov/pubmed/34178964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.674260
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