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Maturation of three-dimensional, hiPSC-derived cardiomyocyte spheroids utilizing cyclic, uniaxial stretch and electrical stimulation

Functional myocardium derived from human induced pluripotent stem cells (hiPSCs) can be impactful for cardiac disease modeling, drug testing, and the repair of injured myocardium. However, when hiPSCs are differentiated into cardiomyocytes, they do not possess characteristics of mature myocytes whic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: LaBarge, Wesley, Mattappally, Saidulu, Kannappan, Ramaswamy, Fast, Vladimir G., Pretorius, Daniëlle, Berry, Joel L., Zhang, Jianyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611624/
https://ncbi.nlm.nih.gov/pubmed/31276558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219442
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