Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

The concept that extracellular vesicles (EVs) from the diet can be absorbed by the intestinal tract of the consuming organism, be bioavailable in various organs, and in-turn exert phenotypic changes is highly debatable. Here, we isolate EVs from both raw and commercial bovine milk and characterize t...

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書誌詳細
出版年:Nat Commun
主要な著者: Samuel, Monisha, Fonseka, Pamali, Sanwlani, Rahul, Gangoda, Lahiru, Chee, Sing Ho, Keerthikumar, Shivakumar, Spurling, Alex, Chitti, Sai V., Zanker, Damien, Ang, Ching-Seng, Atukorala, Ishara, Kang, Taeyoung, Shahi, Sanjay, Marzan, Akbar L., Nedeva, Christina, Vennin, Claire, Lucas, Morghan C., Cheng, Lesley, Herrmann, David, Pathan, Mohashin, Chisanga, David, Warren, Sean C., Zhao, Kening, Abraham, Nidhi, Anand, Sushma, Boukouris, Stephanie, Adda, Christopher G., Jiang, Lanzhou, Shekhar, Tanmay M., Baschuk, Nikola, Hawkins, Christine J., Johnston, Amelia J., Orian, Jacqueline Monique, Hoogenraad, Nicholas J., Poon, Ivan K., Hill, Andrew F., Jois, Markandeya, Timpson, Paul, Parker, Belinda S., Mathivanan, Suresh
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2021
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225634/
https://ncbi.nlm.nih.gov/pubmed/34168137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24273-8
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