Role of backbone strain in de novo design of complex α/β protein structures

We previously elucidated principles for designing ideal proteins with completely consistent local and non-local interactions which have enabled the design of a wide range of new αβ-proteins with four or fewer β-strands. The principles relate local backbone structures to supersecondary-structure pack...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Koga, Nobuyasu, Koga, Rie, Liu, Gaohua, Castellanos, Javier, Montelione, Gaetano T., Baker, David
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225619/
https://ncbi.nlm.nih.gov/pubmed/34168113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24050-7
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