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Autism-Associated Vigilin Depletion Impairs DNA Damage Repair
Vigilin (Vgl1) is essential for heterochromatin formation, chromosome segregation, and mRNA stability and is associated with autism spectrum disorders and cancer: vigilin, for example, can suppress proto-oncogene c-fms expression in breast cancer. Conserved from yeast to humans, vigilin is an RNA-bi...
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| Publicat a: | Mol Cell Biol |
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| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8224237/ https://ncbi.nlm.nih.gov/pubmed/33941620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00082-21 |
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