Autism-Associated Vigilin Depletion Impairs DNA Damage Repair

Vigilin (Vgl1) is essential for heterochromatin formation, chromosome segregation, and mRNA stability and is associated with autism spectrum disorders and cancer: vigilin, for example, can suppress proto-oncogene c-fms expression in breast cancer. Conserved from yeast to humans, vigilin is an RNA-bi...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Banday, Shahid, Pandita, Raj K., Mushtaq, Arjamand, Bacolla, Albino, Mir, Ulfat Syed, Singh, Dharmendra Kumar, Jan, Sadaf, Bhat, Krishna P., Hunt, Clayton R., Rao, Ganesh, Charaka, Vijay K., Tainer, John A., Pandita, Tej K., Altaf, Mohammad
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224237/
https://ncbi.nlm.nih.gov/pubmed/33941620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00082-21
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