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RNA Helicase A/DHX9 Forms Unique Cytoplasmic Antiviral Granules That Restrict Oncolytic Myxoma Virus Replication in Human Cancer Cells

RNA helicase A/DHX9 is required for diverse RNA-related essential cellular functions and antiviral responses and is hijacked by RNA viruses to support their replication. Here, we show that during the late replication stage in human cancer cells of myxoma virus (MYXV), a member of the double-stranded...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Rahman, Masmudur M., Gutierrez-Jensen, Ami D., Glenn, Honor L., Abrantes, Mario, Moussatche, Nissin, McFadden, Grant
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223942/
https://ncbi.nlm.nih.gov/pubmed/33952639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00151-21
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