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RNA Helicase A/DHX9 Forms Unique Cytoplasmic Antiviral Granules That Restrict Oncolytic Myxoma Virus Replication in Human Cancer Cells

RNA helicase A/DHX9 is required for diverse RNA-related essential cellular functions and antiviral responses and is hijacked by RNA viruses to support their replication. Here, we show that during the late replication stage in human cancer cells of myxoma virus (MYXV), a member of the double-stranded...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Rahman, Masmudur M., Gutierrez-Jensen, Ami D., Glenn, Honor L., Abrantes, Mario, Moussatche, Nissin, McFadden, Grant
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223942/
https://ncbi.nlm.nih.gov/pubmed/33952639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00151-21
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