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Methods for the Construction of Recombinant Oncolytic Myxoma Viruses

Myxoma virus (MYXV) has proven to be an effective candidate for oncolytic virotherapy in many preclinical cancer models. As a nonhuman pathogen, MYXV does not need to overcome any preexisting antiviral immunity, and its DNA cannot integrate into the host genome, making it an extremely safe vector. M...

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Publicat a:Methods Mol Biol
Autors principals: Torres-Domínguez, Lino E., Lemos de Matos, Ana, Rahman, Masmudur M., McFadden, Grant
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8082691/
https://ncbi.nlm.nih.gov/pubmed/33108657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-0716-1012-1_4
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