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Construction and Validation of a Reliable Six-Gene Prognostic Signature Based on the TP53 Alteration for Hepatocellular Carcinoma

BACKGROUND: The high mutation rate of TP53 in hepatocellular carcinoma (HCC) makes it an attractive potential therapeutic target. However, the mechanism by which TP53 mutation affects the prognosis of HCC is not fully understood. MATERIAL AND APPROACH: This study downloaded a gene expression profile...

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Опубликовано в: :Front Oncol
Главные авторы: Huo, Junyu, Wu, Liqun, Zang, Yunjin
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222811/
https://ncbi.nlm.nih.gov/pubmed/34178618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618976
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