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Construction and Validation of a Reliable Six-Gene Prognostic Signature Based on the TP53 Alteration for Hepatocellular Carcinoma

BACKGROUND: The high mutation rate of TP53 in hepatocellular carcinoma (HCC) makes it an attractive potential therapeutic target. However, the mechanism by which TP53 mutation affects the prognosis of HCC is not fully understood. MATERIAL AND APPROACH: This study downloaded a gene expression profile...

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Publicat a:Front Oncol
Autors principals: Huo, Junyu, Wu, Liqun, Zang, Yunjin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222811/
https://ncbi.nlm.nih.gov/pubmed/34178618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618976
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