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Construction and Validation of a Reliable Six-Gene Prognostic Signature Based on the TP53 Alteration for Hepatocellular Carcinoma

BACKGROUND: The high mutation rate of TP53 in hepatocellular carcinoma (HCC) makes it an attractive potential therapeutic target. However, the mechanism by which TP53 mutation affects the prognosis of HCC is not fully understood. MATERIAL AND APPROACH: This study downloaded a gene expression profile...

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Publicado en:Front Oncol
Main Authors: Huo, Junyu, Wu, Liqun, Zang, Yunjin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222811/
https://ncbi.nlm.nih.gov/pubmed/34178618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618976
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