Impairing flow-mediated endothelial remodeling reduces extravasation of tumor cells

Tumor progression and metastatic dissemination are driven by cell-intrinsic and biomechanical cues that favor the growth of life-threatening secondary tumors. We recently identified pro-metastatic vascular regions with blood flow profiles that are permissive for the arrest of circulating tumor cells...

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Udgivet i:Sci Rep
Main Authors: Follain, Gautier, Osmani, Naël, Gensbittel, Valentin, Asokan, Nandini, Larnicol, Annabel, Mercier, Luc, Garcia-Leon, Maria Jesus, Busnelli, Ignacio, Pichot, Angelique, Paul, Nicodème, Carapito, Raphaël, Bahram, Seiamak, Lefebvre, Olivier, Goetz, Jacky G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222393/
https://ncbi.nlm.nih.gov/pubmed/34162963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92515-2
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