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The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis

Enzymes can evolve new catalytic activity when environmental changes present them with novel substrates. Despite this seemingly straightforward relationship, factors other than the direct catalytic target can also impact adaptation. Here, we characterize the catalytic activity of a recently evolved...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Anderson, Dave W., Baier, Florian, Yang, Gloria, Tokuriki, Nobuhiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222346/
https://ncbi.nlm.nih.gov/pubmed/34162839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23943-x
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