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Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose tissue chambers capable of modeling the metabolic factors...

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Publicado en:Sci Rep
Autores principales: Slaughter, Victoria L., Rumsey, John W., Boone, Rachel, Malik, Duaa, Cai, Yunqing, Sriram, Narasimhan Narasimhan, Long, Christopher J., McAleer, Christopher W., Lambert, Stephen, Shuler, Michael L., Hickman, J. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222323/
https://ncbi.nlm.nih.gov/pubmed/34162924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92264-2
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