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Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose tissue chambers capable of modeling the metabolic factors...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Slaughter, Victoria L., Rumsey, John W., Boone, Rachel, Malik, Duaa, Cai, Yunqing, Sriram, Narasimhan Narasimhan, Long, Christopher J., McAleer, Christopher W., Lambert, Stephen, Shuler, Michael L., Hickman, J. J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222323/
https://ncbi.nlm.nih.gov/pubmed/34162924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92264-2
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