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Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ
Ischemic heart disease is a leading cause of heart failure and hypoxia inducible factor 1 (HIF1) is a key transcription factor in the response to hypoxic injury. Our lab has developed a mouse model in which a mutated, oxygen-stable form of HIF1α (HIF-PPN) can be inducibly expressed in cardiomyocytes...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8222303/ https://ncbi.nlm.nih.gov/pubmed/34162925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92426-2 |
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