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Inhibiting USP8 overcomes hepatocellular carcinoma resistance via suppressing receptor tyrosine kinases
The ubiquitin-specific protease 8 (USP8) is a prototypic multidomain deubiquitinating enzyme with pleiotropic functions. We investigated the role of USP8 in hepatocellular carcinoma (HCC) by analyzing expression patterns of USP8 in HCC patients, and evaluating its functions and underlying signaling....
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| Veröffentlicht in: | Aging (Albany NY) |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221339/ https://ncbi.nlm.nih.gov/pubmed/34081623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203061 |
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