Formulated Chinese medicine Shaoyao Gancao Tang reduces NLRP1 and NLRP3 in Alzheimer’s disease cell and mouse models for neuroprotection and cognitive improvement

Amyloid β (Aβ) plays a major role in the neurodegeneration of Alzheimer’s disease (AD). The accumulation of misfolded Aβ causes oxidative stress and inflammatory damage leading to apoptotic cell death. Traditional Chinese herbal medicine (CHM) has been widely used in treating neurodegenerative disea...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Chiu, Ya-Jen, Lin, Chih-Hsin, Lee, Ming-Chung, Hsieh-Li, Hsiu Mei, Chen, Chiung-Mei, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221334/
https://ncbi.nlm.nih.gov/pubmed/34106880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203125
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