Novel synthetic chalcone‐coumarin hybrid for Aβ aggregation reduction, antioxidation, and neuroprotection

BACKGROUND: Aggregation of misfolded amyloid β (Aβ) in senile plaques causes oxidative stress and neuronal death in Alzheimer's disease (AD). Compounds possessing antiaggregation and antioxidant properties are promising candidate compounds for AD treatment. METHODS: We examined the potential of...

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Detalhes bibliográficos
Publicado no:CNS Neurosci Ther
Main Authors: Lee, Shin‐Ying, Chiu, Ya‐Jen, Yang, Shu‐Mei, Chen, Chiung‐Mei, Huang, Chin‐Chang, Lee‐Chen, Guey‐Jen, Lin, Wenwei, Chang, Kuo‐Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6490010/
https://ncbi.nlm.nih.gov/pubmed/30596401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13058
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