Formulated Chinese medicine Shaoyao Gancao Tang reduces NLRP1 and NLRP3 in Alzheimer’s disease cell and mouse models for neuroprotection and cognitive improvement

Amyloid β (Aβ) plays a major role in the neurodegeneration of Alzheimer’s disease (AD). The accumulation of misfolded Aβ causes oxidative stress and inflammatory damage leading to apoptotic cell death. Traditional Chinese herbal medicine (CHM) has been widely used in treating neurodegenerative disea...

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Dades bibliogràfiques
Publicat a:Aging (Albany NY)
Autors principals: Chiu, Ya-Jen, Lin, Chih-Hsin, Lee, Ming-Chung, Hsieh-Li, Hsiu Mei, Chen, Chiung-Mei, Wu, Yih-Ru, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221334/
https://ncbi.nlm.nih.gov/pubmed/34106880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203125
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