Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression

Overexpression of interferon induced transmembrane protein-1 (IFITM1) enhances tumor progression in multiple cancers, but its role in triple-negative breast cancer (TNBC) is unknown. Here, we explore the functional significance and regulation of IFITM1 in TNBC and strategies to target its expression...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Provance, Olivia K., Geanes, Eric S., Lui, Asona J., Roy, Anuradha, Holloran, Sean, Gunewardena, Sumedha, Hagan, Christy, Weir, Scott, Lewis-Wambi, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221017/
https://ncbi.nlm.nih.gov/pubmed/34022283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2021.05.006
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