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Interaction between MUC1 and STAT1 drives IFITM1 overexpression in aromatase inhibitor-resistant breast cancer cells and mediates estrogen-induced apoptosis

The human oncoprotein, mucin 1 (MUC1), drives tumorigenesis in breast carcinomas by promoting epithelial-mesenchymal transition (EMT), epigenetic reprogramming, and evasion of immune response. MUC1 interacts with STAT1, through JAK/STAT signaling, and stimulates transcription of interferon-stimulate...

詳細記述

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書誌詳細
出版年:Mol Cancer Res
主要な著者: Escher, Taylor E., Lui, Asona J., Geanes, Eric S., Walter, Katherine R., Tawfik, Ossama, Hagan, Christy R., Lewis-Wambi, Joan
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497545/
https://ncbi.nlm.nih.gov/pubmed/30655323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0916
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