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Engineered Cytokine Signaling to Improve CAR T Cell Effector Function

Adoptive immunotherapy with T cells genetically modified to express chimeric antigen receptors (CARs) is a promising approach to improve outcomes for cancer patients. While CAR T cell therapy is effective for hematological malignancies, there is a need to improve the efficacy of this therapeutic app...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Bell, Matthew, Gottschalk, Stephen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220823/
https://ncbi.nlm.nih.gov/pubmed/34177932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.684642
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